2017 Conference USA Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/08/2018
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 3 | 8.0 | 59 | 2.67 |
| 2 | Rice | 2 | 5.0 | 43 | 2.50 |
| 3 | UTSA | 1 | 4.0 | 22 | 4.00 |
| 4 | Southern Mississippi | 3 | 3.0 | 20 | 1.00 |
| 4 | UTEP | 2 | 2.0 | 20 | 1.00 |
| 6 | UAB | 1 | 2.0 | 18 | 2.00 |
| 7 | Louisiana Tech | 2 | 2.0 | 12 | 1.00 |
| 8 | Old Dominion | 2 | 2.0 | 10 | 1.00 |
| 8 | North Texas | 1 | 1.0 | 10 | 1.00 |
| 10 | Marshall | 1 | 2.0 | 9 | 2.00 |
| 11 | Western Kentucky | 2 | 2.0 | 7 | 1.00 |
| 12 | Charlotte | 1 | 1.0 | 5 | 1.00 |