2016 Mid-American Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 184 | 178 | 52 | 362 | 6.96 | 362.0 |
| 2 | Miami (Ohio) | 1 | 212 | 192 | 50 | 404 | 8.08 | 404.0 |
| 3 | Toledo | 1 | 249 | 196 | 73 | 445 | 6.10 | 445.0 |
| 4 | Ohio | 1 | 114 | 290 | 75 | 404 | 5.39 | 404.0 |
| 5 | Ball State | 1 | 186 | 367 | 62 | 553 | 8.92 | 553.0 |
| 6 | Eastern Michigan | 1 | 163 | 398 | 73 | 561 | 7.68 | 561.0 |
| 7 | Bowling Green | 1 | 359 | 417 | 94 | 776 | 8.26 | 776.0 |
| 8 | Buffalo | 1 | 181 | 445 | 71 | 626 | 8.82 | 626.0 |
| 9 | Central Michigan | 2 | 304 | 458 | 132 | 762 | 5.77 | 381.0 |
| 10 | Akron | 2 | 672 | 499 | 169 | 1171 | 6.93 | 585.5 |
| 11 | Kent State | 3 | 759 | 509 | 226 | 1268 | 5.61 | 422.7 |
| 12 | Northern Illinois | 2 | 539 | 692 | 163 | 1231 | 7.55 | 615.5 |