2022 Mid-American Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 238 | 179 | 64 | 417 | 6.52 | 417.0 |
| 2 | Central Michigan | 1 | 166 | 237 | 71 | 403 | 5.68 | 403.0 |
| 3 | Ohio | 1 | 234 | 338 | 76 | 572 | 7.53 | 572.0 |
| 4 | Ball State | 1 | 218 | 351 | 86 | 569 | 6.62 | 569.0 |
| 5 | Akron | 1 | 238 | 438 | 70 | 676 | 9.66 | 676.0 |
| 6 | Toledo | 1 | 281 | 482 | 78 | 763 | 9.78 | 763.0 |
| 7 | Kent State | 2 | 389 | 665 | 155 | 1054 | 6.80 | 527.0 |
| 8 | Bowling Green | 2 | 314 | 777 | 157 | 1091 | 6.95 | 545.5 |