2016 American Athletic Conference Leaders Total Defense - Games Lost Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | South Florida | 2 | 797 | 378 | 154 | 1175 | 7.63 | 587.5 |
| 2 | Temple | 4 | 719 | 719 | 263 | 1438 | 5.47 | 359.5 |
| 3 | Tulsa | 3 | 926 | 514 | 231 | 1440 | 6.23 | 480.0 |
| 4 | Houston | 4 | 757 | 841 | 269 | 1598 | 5.94 | 399.5 |
| 5 | Navy | 5 | 1178 | 1117 | 350 | 2295 | 6.56 | 459.0 |
| 6 | UCF | 7 | 1448 | 1345 | 535 | 2793 | 5.22 | 399.0 |
| 7 | Memphis | 5 | 1750 | 1279 | 410 | 3029 | 7.39 | 605.8 |
| 8 | Tulane | 8 | 1405 | 1637 | 552 | 3042 | 5.51 | 380.3 |
| 9 | Cincinnati | 8 | 1709 | 1721 | 653 | 3430 | 5.25 | 428.8 |
| 10 | SMU | 7 | 1905 | 1697 | 534 | 3602 | 6.75 | 514.6 |
| 11 | Connecticut | 9 | 1571 | 2351 | 659 | 3922 | 5.95 | 435.8 |
| 12 | East Carolina | 9 | 2290 | 2026 | 650 | 4316 | 6.64 | 479.6 |