2020 American Athletic Conference Leaders Total Defense - Games Lost Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 1 | 45 | 404 | 63 | 449 | 7.13 | 449.0 |
| 2 | Tulsa | 3 | 415 | 560 | 197 | 975 | 4.95 | 325.0 |
| 3 | SMU | 3 | 603 | 784 | 212 | 1387 | 6.54 | 462.3 |
| 4 | Memphis | 3 | 482 | 999 | 218 | 1481 | 6.79 | 493.7 |
| 5 | Houston | 5 | 968 | 1278 | 334 | 2246 | 6.72 | 449.2 |
| 6 | UCF | 4 | 740 | 1538 | 321 | 2278 | 7.10 | 569.5 |
| 7 | Navy | 7 | 1348 | 1355 | 446 | 2703 | 6.06 | 386.1 |
| 8 | Temple | 6 | 1317 | 1390 | 400 | 2707 | 6.77 | 451.2 |
| 9 | East Carolina | 6 | 1510 | 1499 | 429 | 3009 | 7.01 | 501.5 |
| 10 | Tulane | 6 | 1158 | 1940 | 485 | 3098 | 6.39 | 516.3 |
| 11 | South Florida | 8 | 1711 | 1978 | 584 | 3689 | 6.32 | 461.1 |