2016 Conference USA Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 1 | 24 | 183 | 7.63 | 3 | 24.00 | 183.00 |
| 2 | Charlotte | 2 | 69 | 482 | 6.99 | 6 | 34.50 | 241.00 |
| 3 | Western Kentucky | 1 | 39 | 124 | 3.18 | 2 | 39.00 | 124.00 |
| 4 | Marshall | 2 | 82 | 525 | 6.40 | 6 | 41.00 | 262.50 |
| 5 | North Texas | 1 | 43 | 255 | 5.93 | 4 | 43.00 | 255.00 |
| 5 | Rice | 1 | 43 | 373 | 8.67 | 3 | 43.00 | 373.00 |