2016 Conference USA Leaders Rushing Defense - Games in October Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida International | 5 | 154 | 893 | 5.80 | 9 | 30.80 | 178.60 |
| 2 | Charlotte | 4 | 126 | 508 | 4.03 | 9 | 31.50 | 127.00 |
| 3 | Western Kentucky | 5 | 161 | 556 | 3.45 | 5 | 32.20 | 111.20 |
| 4 | Southern Mississippi | 4 | 129 | 762 | 5.91 | 12 | 32.25 | 190.50 |
| 5 | Louisiana Tech | 5 | 163 | 560 | 3.44 | 4 | 32.60 | 112.00 |
| 6 | UTSA | 4 | 143 | 604 | 4.22 | 6 | 35.75 | 151.00 |
| 6 | Rice | 4 | 143 | 716 | 5.01 | 9 | 35.75 | 179.00 |
| 8 | UTEP | 4 | 148 | 863 | 5.83 | 7 | 37.00 | 215.75 |
| 9 | Old Dominion | 4 | 153 | 725 | 4.74 | 7 | 38.25 | 181.25 |
| 10 | Middle Tennessee | 4 | 167 | 693 | 4.15 | 10 | 41.75 | 173.25 |
| 11 | North Texas | 4 | 168 | 673 | 4.01 | 6 | 42.00 | 168.25 |
| 12 | Florida Atlantic | 4 | 184 | 863 | 4.69 | 8 | 46.00 | 215.75 |
| 13 | Marshall | 5 | 235 | 1143 | 4.86 | 14 | 47.00 | 228.60 |