2021 American Athletic Conference Leaders Total Offense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Memphis | 5 | 754 | 1616 | 400 | 2370 | 5.93 | 474.0 |
| 2 | East Carolina | 6 | 818 | 1909 | 468 | 2727 | 5.83 | 454.5 |
| 3 | Tulsa | 7 | 1330 | 1785 | 566 | 3115 | 5.50 | 445.0 |
| 4 | Houston | 9 | 1340 | 2442 | 626 | 3782 | 6.04 | 420.2 |
| 5 | SMU | 6 | 857 | 1597 | 412 | 2454 | 5.96 | 409.0 |
| 6 | Tulane | 6 | 992 | 1270 | 408 | 2262 | 5.54 | 377.0 |
| 7 | UCF | 6 | 1126 | 1109 | 389 | 2235 | 5.75 | 372.5 |
| 8 | Cincinnati | 7 | 849 | 1659 | 447 | 2508 | 5.61 | 358.3 |
| 9 | South Florida | 6 | 803 | 1164 | 406 | 1967 | 4.84 | 327.8 |
| 10 | Temple | 6 | 652 | 967 | 352 | 1619 | 4.60 | 269.8 |
| 11 | Navy | 6 | 1282 | 313 | 386 | 1595 | 4.13 | 265.8 |