2025 Mid-American Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Bowling Green | 1 | 106 | 333 | 53 | 439 | 8.28 | 439.0 |
| 2 | Northern Illinois | 1 | 86 | 254 | 64 | 340 | 5.31 | 340.0 |
| 3 | Toledo | 1 | 220 | 85 | 66 | 305 | 4.62 | 305.0 |
| 4 | Eastern Michigan | 1 | 252 | 240 | 67 | 492 | 7.34 | 492.0 |
| 5 | Massachusetts | 1 | 201 | 234 | 71 | 435 | 6.13 | 435.0 |
| 6 | Akron | 1 | 234 | 494 | 73 | 728 | 9.97 | 728.0 |
| 7 | Buffalo | 1 | 153 | 290 | 79 | 443 | 5.61 | 443.0 |
| 8 | Kent State | 1 | 230 | 371 | 80 | 601 | 7.51 | 601.0 |
| 9 | Ball State | 2 | 317 | 611 | 126 | 928 | 7.37 | 464.0 |
| 10 | Western Michigan | 2 | 343 | 351 | 131 | 694 | 5.30 | 347.0 |
| 11 | Central Michigan | 2 | 505 | 575 | 138 | 1080 | 7.83 | 540.0 |
| 12 | Miami (OH) | 2 | 327 | 447 | 152 | 774 | 5.09 | 387.0 |
| 13 | Ohio | 3 | 444 | 777 | 179 | 1221 | 6.82 | 407.0 |