2025 Mid-American Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 08/28/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Ohio | 1 | 147 | 252 | 59 | 399 | 6.76 | 399.0 |
| 2 | Miami (OH) | 1 | 165 | 188 | 75 | 353 | 4.71 | 353.0 |
| 3 | Buffalo | 1 | 153 | 290 | 79 | 443 | 5.61 | 443.0 |