2025 Mid-American Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Northern Illinois | 2 | 148 | 409 | 119 | 557 | 4.68 | 278.5 |
| 2 | Buffalo | 2 | 157 | 405 | 131 | 562 | 4.29 | 281.0 |
| 3 | Kent State | 2 | 394 | 547 | 146 | 941 | 6.45 | 470.5 |
| 4 | Miami (OH) | 2 | 327 | 447 | 152 | 774 | 5.09 | 387.0 |
| 5 | Bowling Green | 3 | 317 | 645 | 176 | 962 | 5.47 | 320.7 |
| 6 | Ohio | 3 | 444 | 777 | 179 | 1221 | 6.82 | 407.0 |
| 7 | Toledo | 3 | 315 | 379 | 181 | 694 | 3.83 | 231.3 |
| 8 | Western Michigan | 3 | 525 | 575 | 194 | 1100 | 5.67 | 366.7 |
| 9 | Eastern Michigan | 3 | 875 | 702 | 202 | 1577 | 7.81 | 525.7 |
| 10 | Ball State | 3 | 449 | 870 | 205 | 1319 | 6.43 | 439.7 |
| 11 | Massachusetts | 3 | 473 | 828 | 207 | 1301 | 6.29 | 433.7 |
| 11 | Central Michigan | 3 | 580 | 883 | 207 | 1463 | 7.07 | 487.7 |
| 13 | Akron | 3 | 480 | 1095 | 224 | 1575 | 7.03 | 525.0 |