2025 Mid-American Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 12/16/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 182 | 224 | 63 | 406 | 6.44 | 406.0 |
| 2 | Massachusetts | 1 | 268 | 253 | 84 | 521 | 6.20 | 521.0 |
| 3 | Ohio | 1 | 225 | 347 | 63 | 572 | 9.08 | 572.0 |
| 4 | Central Michigan | 1 | 381 | 235 | 80 | 616 | 7.70 | 616.0 |
| 5 | Kent State | 2 | 415 | 541 | 148 | 956 | 6.46 | 478.0 |