2025 Mid-American Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 162 | 196 | 63 | 358 | 5.68 | 358.0 |
| 2 | Ball State | 1 | 224 | 271 | 67 | 495 | 7.39 | 495.0 |
| 3 | Ohio | 1 | 225 | 347 | 63 | 572 | 9.08 | 572.0 |
| 4 | Kent State | 1 | 230 | 371 | 80 | 601 | 7.51 | 601.0 |
| 5 | Central Michigan | 1 | 381 | 235 | 80 | 616 | 7.70 | 616.0 |