2025 Big Ten Conference Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 12/27/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Iowa | 1 | 4 | 4 | 0 | 8 | 8.0 |
| 1 | Michigan State | 1 | 2 | 8 | 0 | 10 | 10.0 |
| 3 | Ohio State | 1 | 5 | 3 | 1 | 9 | 9.0 |
| 3 | Indiana | 2 | 8 | 11 | 1 | 20 | 10.0 |
| 3 | Wisconsin | 2 | 8 | 12 | 1 | 21 | 10.5 |
| 3 | Penn State | 2 | 12 | 14 | 1 | 27 | 13.5 |
| 7 | Illinois | 1 | 5 | 5 | 2 | 12 | 12.0 |
| 7 | Minnesota | 2 | 16 | 7 | 2 | 25 | 12.5 |
| 7 | Rutgers | 2 | 14 | 22 | 2 | 38 | 19.0 |
| 10 | Maryland | 2 | 14 | 19 | 3 | 36 | 18.0 |
| 10 | Purdue | 2 | 21 | 16 | 3 | 40 | 20.0 |
| 12 | Nebraska | 1 | 7 | 2 | 4 | 13 | 13.0 |
| 12 | Washington | 2 | 9 | 20 | 4 | 33 | 16.5 |
| 12 | Northwestern | 3 | 24 | 28 | 4 | 56 | 18.7 |
| 12 | Oregon | 1 | 10 | 9 | 4 | 23 | 23.0 |
| 16 | Michigan | 2 | 8 | 16 | 5 | 29 | 14.5 |
| 16 | USC | 3 | 31 | 24 | 5 | 60 | 20.0 |
| 16 | UCLA | 2 | 21 | 16 | 5 | 42 | 21.0 |