2025 Big Ten Conference Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 09/11/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Michigan State | 1 | 2 | 8 | 0 | 10 | 10.0 |
| 2 | Minnesota | 1 | 4 | 4 | 0 | 8 | 8.0 |
| 2 | Michigan | 1 | 4 | 13 | 4 | 21 | 21.0 |
| 4 | Washington | 1 | 5 | 10 | 2 | 17 | 17.0 |
| 5 | Nebraska | 1 | 7 | 2 | 4 | 13 | 13.0 |
| 6 | Indiana | 2 | 8 | 11 | 1 | 20 | 10.0 |
| 6 | Wisconsin | 2 | 8 | 12 | 1 | 21 | 10.5 |
| 6 | Purdue | 1 | 8 | 4 | 1 | 13 | 13.0 |
| 9 | UCLA | 1 | 9 | 8 | 3 | 20 | 20.0 |
| 10 | Penn State | 2 | 12 | 14 | 1 | 27 | 13.5 |
| 11 | Northwestern | 1 | 13 | 9 | 1 | 23 | 23.0 |
| 12 | Maryland | 2 | 14 | 19 | 3 | 36 | 18.0 |
| 12 | USC | 2 | 14 | 18 | 5 | 37 | 18.5 |
| 12 | Rutgers | 2 | 14 | 22 | 2 | 38 | 19.0 |