2025 Big Ten Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 09/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | USC | 1 | 28 | 52 | 1.86 | 1 | 28.00 | 52.00 |
| 2 | Minnesota | 1 | 24 | 61 | 2.54 | 0 | 24.00 | 61.00 |
| 3 | Michigan State | 1 | 25 | 67 | 2.68 | 1 | 25.00 | 67.00 |
| 4 | Wisconsin | 1 | 22 | 72 | 3.27 | 1 | 22.00 | 72.00 |
| 5 | Illinois | 1 | 24 | 82 | 3.42 | 0 | 24.00 | 82.00 |
| 6 | Iowa | 1 | 30 | 104 | 3.47 | 0 | 30.00 | 104.00 |
| 7 | Michigan | 1 | 40 | 138 | 3.45 | 2 | 40.00 | 138.00 |
| 8 | Ohio State | 1 | 37 | 166 | 4.49 | 0 | 37.00 | 166.00 |
| 9 | Northwestern | 1 | 30 | 176 | 5.87 | 3 | 30.00 | 176.00 |
| 10 | Purdue | 1 | 40 | 178 | 4.45 | 2 | 40.00 | 178.00 |
| 11 | Nebraska | 1 | 30 | 202 | 6.73 | 2 | 30.00 | 202.00 |
| 12 | UCLA | 1 | 54 | 286 | 5.30 | 4 | 54.00 | 286.00 |
| 13 | Oregon | 2 | 79 | 322 | 4.08 | 2 | 39.50 | 161.00 |