2025 Big Ten Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 10/09/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Indiana | 1 | 20 | 2 | 0.10 | 0 | 20.00 | 2.00 |
| 2 | Minnesota | 1 | 30 | 133 | 4.43 | 3 | 30.00 | 133.00 |
| 3 | Michigan | 1 | 40 | 138 | 3.45 | 2 | 40.00 | 138.00 |
| 4 | Washington | 1 | 34 | 149 | 4.38 | 1 | 34.00 | 149.00 |
| 5 | USC | 1 | 35 | 171 | 4.89 | 1 | 35.00 | 171.00 |
| 6 | Penn State | 1 | 39 | 176 | 4.51 | 1 | 39.00 | 176.00 |
| 6 | Northwestern | 1 | 30 | 176 | 5.87 | 3 | 30.00 | 176.00 |
| 8 | Iowa | 2 | 69 | 208 | 3.01 | 0 | 34.50 | 104.00 |
| 9 | Wisconsin | 2 | 56 | 247 | 4.41 | 3 | 28.00 | 123.50 |
| 10 | Nebraska | 1 | 33 | 286 | 8.67 | 3 | 33.00 | 286.00 |
| 11 | Illinois | 1 | 49 | 312 | 6.37 | 3 | 49.00 | 312.00 |
| 12 | Purdue | 2 | 84 | 371 | 4.42 | 8 | 42.00 | 185.50 |