2025 American Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2026
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Tulane | 10 | 30.0 | 220 | 3.00 |
| 2 | USF | 10 | 26.0 | 192 | 2.60 |
| 3 | East Carolina | 9 | 25.0 | 151 | 2.78 |
| 4 | Rice | 11 | 20.0 | 143 | 1.82 |
| 5 | UTSA | 11 | 20.0 | 141 | 1.82 |
| 6 | Navy | 11 | 21.0 | 137 | 1.91 |
| 7 | Florida Atlantic | 10 | 19.0 | 134 | 1.90 |
| 8 | Memphis | 10 | 15.0 | 124 | 1.50 |
| 9 | North Texas | 12 | 18.0 | 113 | 1.50 |
| 10 | Tulsa | 9 | 13.0 | 88 | 1.44 |
| 11 | Army | 11 | 13.0 | 86 | 1.18 |
| 12 | UAB | 10 | 15.0 | 76 | 1.50 |
| 13 | Temple | 9 | 10.0 | 70 | 1.11 |
| 14 | Charlotte | 9 | 8.0 | 55 | 0.89 |