2025 American Conference Leaders First Downs - Games vs. FBS Power 5 Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Memphis | 1 | 16 | 9 | 1 | 26 | 26.0 |
| 2 | North Texas | 1 | 10 | 13 | 2 | 25 | 25.0 |
| 3 | Florida Atlantic | 1 | 7 | 13 | 3 | 23 | 23.0 |
| 4 | Tulane | 3 | 29 | 29 | 5 | 63 | 21.0 |
| 4 | East Carolina | 2 | 12 | 26 | 4 | 42 | 21.0 |
| 4 | Tulsa | 1 | 10 | 11 | 0 | 21 | 21.0 |
| 4 | Charlotte | 1 | 3 | 16 | 2 | 21 | 21.0 |
| 8 | Army | 1 | 17 | 3 | 0 | 20 | 20.0 |
| 9 | UAB | 1 | 1 | 17 | 0 | 18 | 18.0 |
| 10 | USF | 2 | 9 | 20 | 6 | 35 | 17.5 |
| 11 | UTSA | 1 | 8 | 8 | 1 | 17 | 17.0 |
| 12 | Rice | 1 | 12 | 4 | 0 | 16 | 16.0 |
| 13 | Temple | 2 | 11 | 11 | 4 | 26 | 13.0 |