2025 American Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 11/01/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 2 | 226 | 446 | 115 | 672 | 5.84 | 336.0 |
| 2 | Army | 3 | 440 | 485 | 183 | 925 | 5.05 | 308.3 |
| 3 | Tulsa | 3 | 344 | 610 | 205 | 954 | 4.65 | 318.0 |
| 4 | Florida Atlantic | 3 | 405 | 679 | 206 | 1084 | 5.26 | 361.3 |
| 5 | Charlotte | 3 | 378 | 969 | 218 | 1347 | 6.18 | 449.0 |
| 6 | Temple | 4 | 720 | 686 | 237 | 1406 | 5.93 | 351.5 |
| 7 | Memphis | 4 | 382 | 851 | 245 | 1233 | 5.03 | 308.3 |
| 8 | Rice | 4 | 560 | 771 | 253 | 1331 | 5.26 | 332.8 |
| 9 | East Carolina | 4 | 348 | 883 | 258 | 1231 | 4.77 | 307.8 |
| 10 | North Texas | 4 | 515 | 578 | 268 | 1093 | 4.08 | 273.3 |
| 11 | UTSA | 4 | 462 | 1155 | 272 | 1617 | 5.94 | 404.3 |
| 11 | Tulane | 4 | 646 | 1012 | 272 | 1658 | 6.10 | 414.5 |
| 13 | UAB | 4 | 703 | 1136 | 277 | 1839 | 6.64 | 459.8 |
| 14 | USF | 4 | 530 | 1084 | 298 | 1614 | 5.42 | 403.5 |