2025 Atlantic Coast Conference Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 10/24/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Stanford | 2 | 17 | 22 | 5 | 44 | 22.0 |
| 1 | Louisville | 2 | 12 | 16 | 5 | 33 | 16.5 |
| 3 | Duke | 1 | 6 | 17 | 4 | 27 | 27.0 |
| 3 | Virginia Tech | 1 | 10 | 10 | 4 | 24 | 24.0 |
| 3 | Pittsburgh | 1 | 5 | 13 | 4 | 22 | 22.0 |
| 6 | SMU | 1 | 9 | 12 | 3 | 24 | 24.0 |
| 6 | Clemson | 1 | 6 | 8 | 3 | 17 | 17.0 |
| 6 | NC State | 2 | 10 | 20 | 3 | 33 | 16.5 |
| 9 | Boston College | 1 | 13 | 9 | 2 | 24 | 24.0 |
| 9 | Miami (FL) | 2 | 19 | 26 | 2 | 47 | 23.5 |
| 9 | Georgia Tech | 1 | 11 | 6 | 2 | 19 | 19.0 |
| 12 | Florida State | 1 | 27 | 9 | 1 | 37 | 37.0 |
| 12 | Virginia | 1 | 10 | 12 | 1 | 23 | 23.0 |
| 12 | Wake Forest | 1 | 9 | 10 | 1 | 20 | 20.0 |
| 12 | California | 1 | 4 | 12 | 1 | 17 | 17.0 |
| 12 | North Carolina | 1 | 8 | 6 | 1 | 15 | 15.0 |
| 17 | Syracuse | 1 | 6 | 18 | 0 | 24 | 24.0 |