2025 Atlantic Coast Conference Leaders First Downs - Games in August/September Only through 09/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Louisville | 1 | 11 | 15 | 2 | 28 | 28.0 |
| 2 | Georgia Tech | 1 | 17 | 8 | 2 | 27 | 27.0 |
| 3 | Boston College | 1 | 5 | 21 | 0 | 26 | 26.0 |
| 4 | SMU | 1 | 11 | 11 | 3 | 25 | 25.0 |
| 5 | Syracuse | 1 | 9 | 13 | 2 | 24 | 24.0 |
| 6 | Virginia | 1 | 10 | 12 | 1 | 23 | 23.0 |
| 6 | Duke | 1 | 7 | 15 | 1 | 23 | 23.0 |
| 8 | Stanford | 1 | 13 | 4 | 4 | 21 | 21.0 |
| 8 | Pittsburgh | 1 | 8 | 11 | 2 | 21 | 21.0 |
| 8 | NC State | 1 | 7 | 12 | 2 | 21 | 21.0 |
| 11 | Florida State | 1 | 13 | 4 | 3 | 20 | 20.0 |
| 11 | Wake Forest | 1 | 9 | 10 | 1 | 20 | 20.0 |
| 11 | Miami (FL) | 1 | 8 | 11 | 1 | 20 | 20.0 |
| 14 | Virginia Tech | 1 | 9 | 8 | 2 | 19 | 19.0 |
| 15 | California | 1 | 7 | 8 | 0 | 15 | 15.0 |
| 16 | Clemson | 1 | 2 | 11 | 0 | 13 | 13.0 |
| 17 | North Carolina | 1 | 3 | 7 | 0 | 10 | 10.0 |