2025 Big 12 Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 10/28/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Arizona State | 1 | 5.0 | 44 | 5.00 |
| 1 | Arizona | 1 | 5.0 | 22 | 5.00 |
| 3 | Cincinnati | 1 | 4.0 | 23 | 4.00 |
| 3 | Colorado | 2 | 4.0 | 17 | 2.00 |
| 5 | Kansas | 1 | 3.0 | 31 | 3.00 |
| 5 | Houston | 1 | 3.0 | 24 | 3.00 |
| 5 | Texas Tech | 1 | 3.0 | 14 | 3.00 |
| 5 | Iowa State | 1 | 3.0 | 13 | 3.00 |
| 9 | Utah | 1 | 2.0 | 22 | 2.00 |
| 9 | BYU | 1 | 2.0 | 18 | 2.00 |
| 9 | UCF | 1 | 2.0 | 13 | 2.00 |
| 9 | West Virginia | 1 | 2.0 | 6 | 2.00 |