2025 Big 12 Conference Leaders First Downs - Games vs. Ranked Teams Only (AP Poll) through 10/04/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Colorado | 2 | 18 | 14 | 4 | 36 | 18.0 |
| 2 | Cincinnati | 1 | 12 | 7 | 1 | 20 | 20.0 |
| 3 | Arizona | 1 | 9 | 11 | 0 | 20 | 20.0 |
| 4 | West Virginia | 1 | 8 | 7 | 3 | 18 | 18.0 |
| 5 | Baylor | 1 | 7 | 9 | 2 | 18 | 18.0 |
| 5 | Houston | 1 | 7 | 3 | 2 | 12 | 12.0 |
| 7 | Utah | 1 | 6 | 6 | 4 | 16 | 16.0 |
| 7 | Oklahoma State | 1 | 6 | 3 | 0 | 9 | 9.0 |
| 9 | Kansas State | 1 | 4 | 9 | 0 | 13 | 13.0 |
| 10 | TCU | 1 | 2 | 12 | 1 | 15 | 15.0 |
| 10 | Kansas | 1 | 2 | 10 | 1 | 13 | 13.0 |