2025 Big 12 Conference Leaders Opponent First Downs - Games vs. FBS Power 5 Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | TCU | 1 | 3 | 7 | 0 | 10 | 10.0 |
| 1 | BYU | 1 | 4 | 8 | 0 | 12 | 12.0 |
| 1 | Utah | 1 | 6 | 8 | 0 | 14 | 14.0 |
| 1 | Arizona State | 1 | 5 | 12 | 0 | 17 | 17.0 |
| 1 | Cincinnati | 1 | 10 | 13 | 0 | 23 | 23.0 |
| 1 | Kansas | 1 | 12 | 16 | 0 | 28 | 28.0 |
| 7 | Kansas State | 1 | 9 | 9 | 1 | 19 | 19.0 |
| 7 | Oklahoma State | 1 | 14 | 9 | 1 | 24 | 24.0 |
| 9 | Colorado | 1 | 17 | 8 | 2 | 27 | 27.0 |
| 10 | Iowa State | 2 | 12 | 14 | 3 | 29 | 14.5 |
| 11 | Baylor | 2 | 33 | 11 | 4 | 48 | 24.0 |