2025 Big 12 Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 11/04/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UCF | 1 | 27 | 115 | 4.26 | 0 | 27.00 | 115.00 |
| 2 | Texas Tech | 1 | 31 | 101 | 3.26 | 1 | 31.00 | 101.00 |
| 3 | BYU | 1 | 37 | 226 | 6.11 | 1 | 37.00 | 226.00 |
| 4 | Kansas State | 1 | 44 | 187 | 4.25 | 2 | 44.00 | 187.00 |
| 5 | Houston | 1 | 50 | 207 | 4.14 | 2 | 50.00 | 207.00 |
| 5 | Baylor | 1 | 50 | 265 | 5.30 | 3 | 50.00 | 265.00 |
| 7 | Arizona | 1 | 51 | 258 | 5.06 | 3 | 51.00 | 258.00 |
| 8 | Cincinnati | 1 | 53 | 267 | 5.04 | 3 | 53.00 | 267.00 |
| 9 | Iowa State | 2 | 62 | 363 | 5.85 | 5 | 31.00 | 181.50 |
| 10 | Arizona State | 2 | 69 | 385 | 5.58 | 7 | 34.50 | 192.50 |
| 11 | West Virginia | 2 | 89 | 407 | 4.57 | 5 | 44.50 | 203.50 |
| 12 | Oklahoma State | 3 | 107 | 543 | 5.07 | 9 | 35.67 | 181.00 |
| 13 | Utah | 3 | 109 | 581 | 5.33 | 5 | 36.33 | 193.67 |
| 14 | Kansas | 3 | 124 | 848 | 6.84 | 8 | 41.33 | 282.67 |
| 15 | Colorado | 3 | 134 | 950 | 7.09 | 8 | 44.67 | 316.67 |