2025 Big 12 Conference Leaders Interceptions - Games in August/September Only through 10/25/2025
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jackson Bennee | Utah | SO | S | 5 | 3 | 103 | 1 | 0.60 |
| 1 | Evan Johnson | BYU | JR | CB | 4 | 2 | 15 | 1 | 0.50 |
| 1 | Jay'Vion Cole | Arizona | JR | DB | 3 | 1 | 27 | 1 | 0.33 |
| 1 | Skyler Gill-Howard | Texas Tech | SR | DL | 4 | 1 | 55 | 1 | 0.25 |
| 1 | Will James | Houston | SO | DB | 4 | 1 | 37 | 1 | 0.25 |
| 1 | Bud Clark | TCU | SR | S | 4 | 1 | 25 | 1 | 0.25 |