2025 Big 12 Conference Leaders Passes Defended - Games vs. Conference Teams Only through 09/13/2025
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Genesis Smith | Arizona | JR | DB | 1 | 0 | 3 | 3 | 3.00 |
| 2 | Zashon Rich | Kansas St | SO | CB | 2 | 0 | 3 | 3 | 1.50 |
| 3 | Qua Moss | Kansas St | JR | S | 2 | 1 | 1 | 2 | 1.00 |
| 3 | Donovan McIntosh | Kansas St | SO | CB | 2 | 0 | 2 | 2 | 1.00 |
| 3 | Wrook Brown | Houston | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 3 | Blake Thompson | Houston | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 3 | Jay'Vion Cole | Arizona | JR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Ayden Garnes | Arizona | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Michael Dansby | Arizona | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Dalton Johnson | Arizona | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Leroy Palu | Arizona | JR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Makari Vickers | Colorado | SO | CB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Tawfiq Byard | Colorado | SO | S | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Latrell McCutchin Sr. | Houston | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Carlos Allen Jr. | Houston | SR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Jeremiah Cooper | Iowa State | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Ta’Shawn James | Iowa State | SO | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Marcus Neal Jr. | Iowa State | SO | DB | 1 | 0 | 1 | 1 | 1.00 |
| 3 | Ikenna Ezeogu | Iowa State | JR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 20 | Wesley Fair | Kansas St | SO | S | 2 | 0 | 1 | 1 | 0.50 |
| 20 | Desmond Purnell | Kansas St | SR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 20 | Travis Bates | Kansas St | JR | DE | 2 | 0 | 1 | 1 | 0.50 |
| 20 | Austin Romaine | Kansas St | JR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 20 | Uso Seumalo | Kansas St | SR | DT | 2 | 0 | 1 | 1 | 0.50 |
Note: To qualify, player must have played in 75% of his team's games.