2025 Big 12 Conference Leaders Sacks - Games vs. Conference Teams Only through 09/12/2025
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tobi Osunsanmi | Kansas St | JR | DE | 2 | 2.0 | 18 | 1.00 |
| 2 | Corey Platt Jr. | Houston | SO | LB | 1 | 1.0 | 12 | 1.00 |
| 2 | Kooper Ebel | Iowa State | JR | LB | 1 | 1.0 | 12 | 1.00 |
| 2 | Qua Moss | Kansas St | JR | S | 2 | 1.0 | 10 | 0.50 |
| 2 | Chiddi Obiazor | Kansas St | SO | DE | 2 | 1.0 | 6 | 0.50 |
| 2 | Jordan Allen | Kansas St | SO | DE | 2 | 1.0 | 4 | 0.50 |
| 2 | Eddie Walls III | Houston | SR | DL | 1 | 1.0 | 2 | 1.00 |
| 2 | Khalil Laufau | Houston | JR | DL | 1 | 1.0 | 1 | 1.00 |
| 9 | Damian Ilalio | Kansas St | SR | DT | 2 | 0.5 | 6 | 0.25 |
| 9 | Tawfiq Byard | Colorado | SO | S | 1 | 0.5 | 5 | 0.50 |
| 9 | Brandon Davis-Swain | Colorado | FR | DE | 1 | 0.5 | 5 | 0.50 |
| 9 | Travis Bates | Kansas St | JR | DE | 2 | 0.5 | 5 | 0.25 |
| 9 | Treydan Stukes | Arizona | SR | DB | 1 | 0.5 | 4 | 0.50 |
| 9 | Deshawn McKnight | Arizona | SR | DL | 1 | 0.5 | 4 | 0.50 |
| 9 | Amari McNeill | Colorado | SR | DT | 1 | 0.5 | 1 | 0.50 |
| 9 | Alexander McPherson | Colorado | FR | DE | 1 | 0.5 | 1 | 0.50 |