2025 Conference USA Leaders First Downs - Games in August/September Only through 10/09/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 5 | 35 | 72 | 10 | 117 | 23.4 |
| 2 | Missouri State | 5 | 29 | 52 | 10 | 91 | 18.2 |
| 3 | Middle Tennessee State | 5 | 28 | 51 | 9 | 88 | 17.6 |
| 4 | UTEP | 5 | 23 | 48 | 11 | 82 | 16.4 |
| 5 | Delaware | 4 | 41 | 46 | 11 | 98 | 24.5 |
| 6 | Kennesaw State | 5 | 46 | 44 | 6 | 96 | 19.2 |
| 7 | New Mexico State | 4 | 13 | 43 | 11 | 67 | 16.8 |
| 8 | FIU | 4 | 32 | 36 | 5 | 73 | 18.3 |
| 9 | Liberty | 5 | 46 | 35 | 5 | 86 | 17.2 |
| 10 | Jacksonville State | 5 | 71 | 32 | 5 | 108 | 21.6 |
| 11 | Louisiana Tech | 5 | 45 | 28 | 11 | 84 | 16.8 |
| 12 | Sam Houston State | 4 | 22 | 27 | 11 | 60 | 15.0 |