2025 Conference USA Leaders First Downs - Games vs. Non-Conference Teams Only through 11/22/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | New Mexico State | 4 | 19 | 47 | 12 | 78 | 19.5 |
| 2 | Delaware | 4 | 39 | 46 | 8 | 93 | 23.3 |
| 3 | Western Kentucky | 4 | 26 | 45 | 9 | 80 | 20.0 |
| 4 | Missouri State | 4 | 20 | 43 | 7 | 70 | 17.5 |
| 5 | UTEP | 4 | 17 | 40 | 10 | 67 | 16.8 |
| 6 | FIU | 4 | 34 | 37 | 6 | 77 | 19.3 |
| 6 | Middle Tennessee State | 4 | 19 | 37 | 8 | 64 | 16.0 |
| 8 | Kennesaw State | 4 | 38 | 36 | 5 | 79 | 19.8 |
| 9 | Jacksonville State | 4 | 56 | 29 | 5 | 90 | 22.5 |
| 10 | Liberty | 4 | 36 | 25 | 5 | 66 | 16.5 |
| 11 | Sam Houston State | 4 | 21 | 23 | 10 | 54 | 13.5 |
| 12 | Louisiana Tech | 4 | 25 | 19 | 7 | 51 | 12.8 |