2025 Conference USA Leaders First Downs - Games vs. Non-Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Delaware | 2 | 16 | 27 | 2 | 45 | 22.5 |
| 1 | Western Kentucky | 2 | 13 | 27 | 4 | 44 | 22.0 |
| 3 | New Mexico State | 2 | 7 | 22 | 9 | 38 | 19.0 |
| 4 | FIU | 2 | 20 | 19 | 3 | 42 | 21.0 |
| 4 | Missouri State | 2 | 10 | 19 | 0 | 29 | 14.5 |
| 6 | UTEP | 2 | 12 | 18 | 3 | 33 | 16.5 |
| 7 | Sam Houston State | 2 | 16 | 15 | 8 | 39 | 19.5 |
| 7 | Middle Tennessee State | 2 | 10 | 15 | 2 | 27 | 13.5 |
| 9 | Kennesaw State | 2 | 14 | 11 | 3 | 28 | 14.0 |
| 10 | Liberty | 1 | 11 | 10 | 1 | 22 | 22.0 |
| 11 | Louisiana Tech | 2 | 15 | 7 | 4 | 26 | 13.0 |
| 12 | Jacksonville State | 1 | 11 | 5 | 2 | 18 | 18.0 |