2025 Conference USA Leaders Sacks - Games vs. Unranked Teams Only (AP Poll) through 11/01/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UTEP | 7 | 20.0 | 144 | 2.86 |
| 2 | Kennesaw State | 7 | 18.0 | 85 | 2.57 |
| 3 | Jacksonville State | 8 | 17.0 | 103 | 2.13 |
| 4 | Middle Tennessee State | 8 | 16.0 | 102 | 2.00 |
| 4 | New Mexico State | 8 | 16.0 | 95 | 2.00 |
| 6 | FIU | 8 | 15.0 | 108 | 1.88 |
| 7 | Delaware | 8 | 14.0 | 101 | 1.75 |
| 7 | Louisiana Tech | 8 | 14.0 | 95 | 1.75 |
| 9 | Missouri State | 7 | 12.0 | 90 | 1.71 |
| 10 | Liberty | 8 | 11.0 | 62 | 1.38 |
| 11 | Sam Houston State | 7 | 8.0 | 50 | 1.14 |
| 12 | Western Kentucky | 9 | 10.0 | 64 | 1.11 |