2025 Conference USA Leaders Sacks - Games vs. FBS Teams With Winning Record Only through 11/01/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Kennesaw State | 4 | 8.0 | 35 | 2.00 |
| 1 | UTEP | 3 | 6.0 | 48 | 2.00 |
| 1 | Jacksonville State | 1 | 2.0 | 21 | 2.00 |
| 4 | FIU | 4 | 7.0 | 50 | 1.75 |
| 4 | New Mexico State | 4 | 7.0 | 37 | 1.75 |
| 6 | Middle Tennessee State | 3 | 5.0 | 44 | 1.67 |
| 6 | Missouri State | 3 | 5.0 | 41 | 1.67 |
| 8 | Louisiana Tech | 4 | 6.0 | 39 | 1.50 |
| 9 | Delaware | 3 | 4.0 | 27 | 1.33 |
| 10 | Sam Houston State | 6 | 7.0 | 35 | 1.17 |
| 11 | Western Kentucky | 2 | 1.0 | 0 | 0.50 |
| 12 | Liberty | 3 | 1.0 | 3 | 0.33 |