2024 Big 12 Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Colorado | 11 | 13 | 48 | 61 | 5.55 |
| 2 | Arizona State | 12 | 13 | 47 | 60 | 5.00 |
| 3 | BYU | 11 | 20 | 37 | 57 | 5.18 |
| 4 | Utah | 10 | 9 | 45 | 54 | 5.40 |
| 5 | Iowa State | 12 | 12 | 38 | 50 | 4.17 |
| 6 | Baylor | 11 | 12 | 36 | 48 | 4.36 |
| 7 | Kansas State | 11 | 9 | 38 | 47 | 4.27 |
| 8 | Oklahoma State | 10 | 10 | 35 | 45 | 4.50 |
| 8 | TCU | 11 | 7 | 38 | 45 | 4.09 |
| 10 | Kansas | 10 | 11 | 33 | 44 | 4.40 |
| 11 | Texas Tech | 11 | 11 | 27 | 38 | 3.45 |
| 12 | Houston | 10 | 10 | 25 | 35 | 3.50 |
| 13 | Arizona | 10 | 6 | 25 | 31 | 3.10 |
| 14 | Cincinnati | 10 | 4 | 26 | 30 | 3.00 |
| 14 | West Virginia | 11 | 5 | 25 | 30 | 2.73 |
| 16 | UCF | 10 | 5 | 23 | 28 | 2.80 |