2022 National Leaders Long All Purpose Plays - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Donovan Edwards | Michigan | SO | RB | 3 | 4 | 4 | 4 | 3 | 2 | 1 | 0 |
| 2 | Israel Abanikanda | Pittsburgh | JR | RB | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Braelon Allen | Wisconsin | SO | RB | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Monaray Baldwin | Baylor | SO | WR | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Brock Bowers | Georgia | SO | TE | 7 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Dalevon Campbell | Nevada | JR | WR | 1 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Ja'Had Carter | Syracuse | SO | DB | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Logan Diggs | Notre Dame | SO | RB | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Trevor Etienne | Florida | FR | RB | 7 | 6 | 4 | 1 | 1 | 1 | 1 | 0 |
| 2 | O'Donnell Fortune | S Carolina | SO | DB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Antoine Green | N Carolina | SR | WR | 3 | 3 | 3 | 3 | 2 | 1 | 1 | 0 |
| 2 | Taylen Green | Boise St | FR | QB | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Xzavier Henderson | Florida | SO | WR | 6 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | R.J. Hubert | Utah | SR | S | 6 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Jalin Hyatt | Tennessee | JR | WR | 5 | 4 | 3 | 2 | 2 | 1 | 0 | 0 |
| 2 | Jha'Quan Jackson | Tulane | JR | WR | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Sam James | WVU | JR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Chris Jefferson | Purdue | SR | S | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Cornelius Johnson | Michigan | SR | WR | 3 | 3 | 2 | 2 | 2 | 1 | 0 | 0 |
| 2 | Quentin Johnston | TCU | JR | WR | 5 | 8 | 5 | 4 | 1 | 1 | 0 | 0 |
| 2 | KeAndre Lambert-Smith | Penn State | SO | WR | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Logan Loya | UCLA | JR | WR | 5 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Francisco Mauigoa | Wash St | SO | LB | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Jase McClellan | Alabama | JR | RB | 5 | 2 | 2 | 2 | 2 | 1 | 1 | 0 |
| 2 | Ladd McConkey | Georgia | SO | WR | 7 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Kendre Miller | TCU | JR | RB | 4 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Benjamin Morrison | Notre Dame | FR | CB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Clark Phillips III | Utah | SO | CB | 5 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Ja'Lynn Polk | Washington | FR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Courtney Reese | UNLV | JR | RB | 2 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Brenden Rice | USC | JR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Anthony Richardson | Florida | SO | QB | 6 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 2 | Dorian Singer | Arizona | SO | WR | 6 | 4 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Nicholas Singleton | Penn State | FR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Arian Smith | Georgia | SO | WR | 5 | 3 | 3 | 2 | 1 | 1 | 0 | 0 |
| 2 | Christopher Smith | Georgia | SR | DB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Dequan Stanley | S Florida | FR | WR | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Charlie Thomas | Ga Tech | SR | LB | 4 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Jordyn Tyson | Colorado | FR | WR | 4 | 3 | 2 | 2 | 1 | 1 | 1 | 0 |
| 2 | Deuce Vaughn | Kansas St | JR | RB | 5 | 3 | 3 | 1 | 1 | 1 | 1 | 0 |
| 2 | Antwane Wells Jr. | S Carolina | JR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Brayden Willis | Oklahoma | SR | TE | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Michael Wilson | Stanford | SR | WR | 5 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |