2022 American Athletic Conference Leaders Tackles For Loss - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | University of Houston | 11 | 74.0 | 259 | 6.73 |
| 2 | Temple University | 9 | 60.0 | 238 | 6.67 |
| 3 | University of Cincinnati | 9 | 59.0 | 226 | 6.56 |
| 4 | East Carolina University | 11 | 66.0 | 261 | 6.00 |
| 5 | U.S. Naval Academy | 11 | 65.0 | 263 | 5.91 |
| 6 | University of Memphis | 11 | 56.0 | 183 | 5.09 |
| 7 | University of Central Florida | 10 | 50.0 | 199 | 5.00 |
| 8 | The University of Tulsa | 10 | 48.0 | 168 | 4.80 |
| 9 | University of South Florida | 9 | 42.0 | 122 | 4.67 |
| 10 | Southern Methodist University | 10 | 45.0 | 206 | 4.50 |
| 11 | Tulane University | 11 | 48.0 | 178 | 4.36 |