2022 American Athletic Conference Leaders Tackles For Loss - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | University of Cincinnati | 12 | 89.0 | 354 | 7.42 |
| 1 | University of Houston | 12 | 89.0 | 316 | 7.42 |
| 3 | Temple University | 12 | 88.0 | 341 | 7.33 |
| 4 | U.S. Naval Academy | 11 | 68.0 | 273 | 6.18 |
| 5 | East Carolina University | 12 | 68.0 | 269 | 5.67 |
| 6 | University of Central Florida | 12 | 67.0 | 241 | 5.58 |
| 7 | The University of Tulsa | 11 | 56.0 | 197 | 5.09 |
| 7 | University of Memphis | 11 | 56.0 | 183 | 5.09 |
| 9 | University of South Florida | 11 | 54.0 | 176 | 4.91 |
| 10 | Southern Methodist University | 11 | 51.0 | 237 | 4.64 |
| 11 | Tulane University | 12 | 54.0 | 199 | 4.50 |