2022 American Athletic Conference Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | University of Cincinnati | 3 | 27.0 | 111 | 9.00 |
| 2 | University of Houston | 2 | 20.0 | 83 | 10.00 |
| 3 | University of Central Florida | 3 | 17.0 | 44 | 5.67 |
| 4 | Tulane University | 2 | 15.0 | 29 | 7.50 |
| 5 | Temple University | 2 | 13.0 | 54 | 6.50 |
| 6 | Southern Methodist University | 2 | 12.0 | 62 | 6.00 |
| 7 | University of South Florida | 2 | 9.0 | 22 | 4.50 |
| 8 | The University of Tulsa | 1 | 6.0 | 11 | 6.00 |
| 9 | East Carolina University | 1 | 4.0 | 7 | 4.00 |
| 10 | University of Memphis | 1 | 3.0 | 17 | 3.00 |