2022 American Athletic Conference Leaders Tackles For Loss - Games in August/September Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Houston | 5 | 37.0 | 157 | 7.40 |
| 2 | Temple | 4 | 36.0 | 134 | 9.00 |
| 3 | Cincinnati | 4 | 35.0 | 146 | 8.75 |
| 4 | UCF | 4 | 28.0 | 99 | 7.00 |
| 5 | South Florida | 4 | 27.0 | 96 | 6.75 |
| 5 | Tulane | 5 | 27.0 | 77 | 5.40 |
| 7 | SMU | 4 | 26.0 | 121 | 6.50 |
| 8 | Navy | 3 | 22.0 | 80 | 7.33 |
| 9 | Tulsa | 4 | 21.0 | 51 | 5.25 |
| 10 | East Carolina | 4 | 20.0 | 87 | 5.00 |
| 11 | Memphis | 4 | 18.0 | 57 | 4.50 |