2022 American Athletic Conference Leaders Passes Defended - Games Lost Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Houston | 5 | 3 | 18 | 21 | 4.20 |
| 2 | Tulane | 2 | 0 | 8 | 8 | 4.00 |
| 3 | Tulsa | 7 | 2 | 22 | 24 | 3.43 |
| 4 | Temple | 9 | 3 | 26 | 29 | 3.22 |
| 5 | Memphis | 6 | 3 | 15 | 18 | 3.00 |
| 5 | East Carolina | 5 | 3 | 12 | 15 | 3.00 |
| 7 | UCF | 5 | 1 | 13 | 14 | 2.80 |
| 8 | South Florida | 11 | 5 | 23 | 28 | 2.55 |
| 9 | SMU | 6 | 1 | 13 | 14 | 2.33 |
| 10 | Cincinnati | 4 | 2 | 7 | 9 | 2.25 |
| 11 | Navy | 8 | 1 | 14 | 15 | 1.88 |