2022 American Athletic Conference Leaders First Downs - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Houston | 8 | 56 | 139 | 8 | 203 | 25.4 |
| 2 | SMU | 8 | 78 | 100 | 21 | 199 | 24.9 |
| 3 | UCF | 9 | 101 | 109 | 8 | 218 | 24.2 |
| 4 | Memphis | 8 | 61 | 105 | 16 | 182 | 22.8 |
| 5 | East Carolina | 8 | 61 | 102 | 11 | 174 | 21.8 |
| 6 | Tulane | 9 | 93 | 90 | 9 | 192 | 21.3 |
| 7 | USF | 8 | 79 | 76 | 13 | 168 | 21.0 |
| 8 | Temple | 8 | 25 | 122 | 13 | 160 | 20.0 |
| 9 | Tulsa | 8 | 57 | 78 | 19 | 154 | 19.3 |
| 10 | Navy | 8 | 122 | 20 | 10 | 152 | 19.0 |
| 11 | Cincinnati | 8 | 55 | 84 | 4 | 143 | 17.9 |