2022 American Athletic Conference Leaders Scoring Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | University of Central Florida | 12 | 29 | 17 | 24 | 3 | 0 | 255 | 21.3 |
| 1 | Tulane University | 12 | 32 | 11 | 31 | 0 | 0 | 256 | 21.3 |
| 1 | University of Memphis | 11 | 32 | 9 | 26 | 3 | 0 | 251 | 22.8 |
| 1 | U.S. Naval Academy | 11 | 29 | 18 | 27 | 1 | 0 | 257 | 23.4 |
| 1 | East Carolina University | 12 | 41 | 13 | 38 | 3 | 0 | 329 | 27.4 |
| 1 | Temple University | 12 | 44 | 14 | 43 | 1 | 0 | 351 | 29.3 |
| 1 | University of Houston | 12 | 48 | 20 | 41 | 1 | 0 | 391 | 32.6 |
| 8 | Southern Methodist University | 11 | 42 | 15 | 36 | 2 | 1 | 339 | 30.8 |
| 8 | The University of Tulsa | 11 | 44 | 20 | 42 | 1 | 1 | 370 | 33.6 |
| 8 | University of South Florida | 11 | 58 | 14 | 55 | 1 | 1 | 449 | 40.8 |
| 11 | University of Cincinnati | 12 | 30 | 10 | 27 | 0 | 2 | 241 | 20.1 |