2022 American Athletic Conference Leaders Interceptions - Games in August/September Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ja'Von Hicks | Cincinnati | SR | S | 4 | 1 | 45 | 1 | 0.25 |
| 1 | Layton Jordan | Temple | JR | OLB | 4 | 1 | 41 | 1 | 0.25 |
| 1 | Jaylon Allen | Memphis | SR | DL | 4 | 1 | 39 | 1 | 0.25 |
| 1 | Xavier Cullens | Memphis | SR | LB | 4 | 1 | 37 | 1 | 0.25 |
| 1 | Jayce Rogers | Houston | SR | DB | 5 | 1 | 54 | 1 | 0.20 |