2022 Atlantic Coast Conference Leaders Rushing Defense - Games in December/January Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 1 | 38 | 55 | 1.45 | 0 | 38.00 | 55.00 |
| 2 | North Carolina State | 1 | 41 | 76 | 1.85 | 0 | 41.00 | 76.00 |
| 3 | Syracuse | 1 | 33 | 77 | 2.33 | 1 | 33.00 | 77.00 |
| 4 | Wake Forest | 1 | 33 | 114 | 3.45 | 1 | 33.00 | 114.00 |
| 5 | Duke | 1 | 36 | 128 | 3.56 | 2 | 36.00 | 128.00 |
| 5 | Pittsburgh | 1 | 28 | 128 | 4.57 | 2 | 28.00 | 128.00 |
| 7 | Clemson | 2 | 74 | 237 | 3.20 | 2 | 37.00 | 118.50 |
| 8 | Florida State | 1 | 60 | 253 | 4.22 | 3 | 60.00 | 253.00 |
| 9 | North Carolina | 2 | 53 | 277 | 5.23 | 5 | 26.50 | 138.50 |