2022 Atlantic Coast Conference Leaders Rushing Defense - Games in November Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 4 | 103 | 186 | 1.81 | 1 | 25.75 | 46.50 |
| 2 | North Carolina State | 4 | 127 | 326 | 2.57 | 4 | 31.75 | 81.50 |
| 3 | Virginia | 2 | 88 | 351 | 3.99 | 3 | 44.00 | 175.50 |
| 4 | Duke | 4 | 119 | 405 | 3.40 | 2 | 29.75 | 101.25 |
| 5 | Wake Forest | 4 | 138 | 487 | 3.53 | 5 | 34.50 | 121.75 |
| 6 | Virginia Tech | 3 | 115 | 490 | 4.26 | 4 | 38.33 | 163.33 |
| 7 | Clemson | 4 | 132 | 498 | 3.77 | 5 | 33.00 | 124.50 |
| 8 | North Carolina | 4 | 154 | 601 | 3.90 | 9 | 38.50 | 150.25 |
| 9 | Florida State | 4 | 145 | 615 | 4.24 | 3 | 36.25 | 153.75 |
| 10 | Louisville | 4 | 154 | 624 | 4.05 | 4 | 38.50 | 156.00 |
| 11 | Syracuse | 4 | 176 | 692 | 3.93 | 5 | 44.00 | 173.00 |
| 12 | Georgia Tech | 4 | 157 | 782 | 4.98 | 7 | 39.25 | 195.50 |
| 13 | Miami (Florida) | 4 | 158 | 807 | 5.11 | 9 | 39.50 | 201.75 |
| 14 | Boston College | 4 | 162 | 871 | 5.38 | 11 | 40.50 | 217.75 |