2022 Big 12 Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Tre'Vius Hodges-Tomlinson | TCU | SR | CB | 3 | 0 | 5 | 5 | 1.67 |
| 2 | Anthony Cook | Texas | SR | DB | 1 | 0 | 3 | 3 | 3.00 |
| 2 | Millard Bradford | TCU | SR | S | 3 | 0 | 3 | 3 | 1.00 |
| 4 | Kendal Daniels | Okla St | FR | S | 1 | 0 | 2 | 2 | 2.00 |
| 4 | Terrance Brooks | Texas | FR | DB | 1 | 0 | 2 | 2 | 2.00 |
| 4 | Josh Newton | TCU | JR | CB | 3 | 0 | 2 | 2 | 0.67 |
| 7 | Trey Rucker | Okla St | SR | S | 1 | 1 | 1 | 2 | 2.00 |
| 7 | Julius Brents | Kansas St | SR | CB | 2 | 1 | 1 | 2 | 1.00 |
| 7 | Bud Clark | TCU | SO | S | 3 | 1 | 1 | 2 | 0.67 |
| 7 | Dee Winters | TCU | SR | LB | 3 | 1 | 1 | 2 | 0.67 |
| 7 | Mello Dotson | Kansas | SO | CB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Cobee Bryant | Kansas | SO | CB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Hayden Hatcher | Kansas | SR | DE | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Eddie Wilson | Kansas | SR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Kenny Logan Jr. | Kansas | SR | S | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Stephon Johnson Jr. | Okla St | FR | WR | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Justin Broiles | Oklahoma | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Danny Stutsman | Oklahoma | SO | LB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Woodi Washington | Oklahoma | JR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | C.J. Coldon | Oklahoma | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Adrian Frye | Texas Tech | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Malik Dunlap | Texas Tech | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Kosi Eldridge | Texas Tech | SR | LB | 1 | 0 | 1 | 1 | 1.00 |
| 7 | T'Vondre Sweat | Texas | SR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 7 | Robert Hentz II | Kansas St | SR | NG | 2 | 0 | 1 | 1 | 0.50 |
| 7 | Ekow Boye-Doe | Kansas St | SR | CB | 2 | 0 | 1 | 1 | 0.50 |
| 7 | Austin Moore | Kansas St | JR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 7 | Jacob Parrish | Kansas St | FR | CB | 2 | 0 | 1 | 1 | 0.50 |
| 7 | Abe Camara | TCU | JR | S | 3 | 0 | 1 | 1 | 0.33 |
| 7 | Dylan Horton | TCU | SR | DL | 3 | 0 | 1 | 1 | 0.33 |