2022 Big 12 Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Trey Rucker | Okla St | SR | S | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Julius Brents | Kansas St | SR | CB | 2 | 1 | 1 | 2 | 1.00 |
| 1 | Bud Clark | TCU | SO | S | 3 | 1 | 1 | 2 | 0.67 |
| 1 | Dee Winters | TCU | SR | LB | 3 | 1 | 1 | 2 | 0.67 |
| 1 | O.J. Burroughs | Kansas | SO | S | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Billy Bowman Jr. | Oklahoma | SO | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Tyler Owens | Texas Tech | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Marquis Waters | Texas Tech | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Dadrion Taylor-Demerson | Texas Tech | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Jerrin Thompson | Texas | JR | DB | 1 | 1 | 0 | 1 | 1.00 |