2022 Big 12 Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | D'Shawn Jamison | Texas | SR | DB | 2 | 1 | 2 | 3 | 1.50 |
| 1 | Daniel Green | Kansas St | SR | LB | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Josh Newton | TCU | JR | CB | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Justin Harrington | Oklahoma | SR | DB | 2 | 1 | 1 | 2 | 1.00 |
| 1 | Anthony Johnson Jr. | Iowa State | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Colby Reeder | Iowa State | SR | LB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Kobe Savage | Kansas St | JR | S | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Kenny Logan Jr. | Kansas | SR | S | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Kendal Daniels | Okla St | FR | S | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Abe Camara | TCU | JR | S | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Reggie Pearson Jr. | Texas Tech | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Gentry Williams | Oklahoma | FR | DB | 2 | 1 | 0 | 1 | 0.50 |
| 1 | Jahdae Barron | Texas | JR | DB | 2 | 1 | 0 | 1 | 0.50 |