2022 Big 12 Conference Leaders Sacks - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Dylan Horton | TCU | SR | DL | 3 | 6.0 | 54 | 2.00 |
| 2 | Dee Winters | TCU | SR | LB | 3 | 1.0 | 12 | 0.33 |
| 2 | Daniel Green | Kansas St | SR | LB | 2 | 1.0 | 11 | 0.50 |
| 2 | Nathan Latu | Okla St | SR | DE | 1 | 1.0 | 9 | 1.00 |
| 2 | Felix Anudike-Uzomah | Kansas St | JR | DE | 2 | 1.0 | 9 | 0.50 |
| 2 | Krishon Merriweather | Texas Tech | SR | LB | 1 | 1.0 | 7 | 1.00 |
| 2 | Danny Stutsman | Oklahoma | SO | LB | 1 | 1.0 | 6 | 1.00 |
| 2 | Lyrik Rawls | Okla St | FR | S | 1 | 1.0 | 4 | 1.00 |
| 2 | VJ Payne | Kansas St | FR | S | 2 | 1.0 | 4 | 0.50 |
| 2 | Isaac Smith | Texas Tech | FR | OLB | 1 | 1.0 | 2 | 1.00 |
| 11 | Isaiah Coe | Oklahoma | JR | DL | 1 | 0.5 | 3 | 0.50 |
| 11 | Josh Ellison | Oklahoma | SR | DL | 1 | 0.5 | 3 | 0.50 |