2022 Big 12 Conference Leaders Sacks - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Dylan Horton | TCU | SR | DL | 5 | 4.0 | 38 | 0.80 |
| 1 | Reggie Grimes II | Oklahoma | JR | DL | 3 | 4.0 | 31 | 1.33 |
| 1 | Lonnie Phelps | Kansas | JR | DE | 4 | 4.0 | 25 | 1.00 |
| 4 | Dante Stills | WVU | SR | DL | 3 | 2.5 | 21 | 0.83 |
| 4 | Ethan Downs | Oklahoma | SO | DL | 4 | 2.5 | 15 | 0.63 |
| 4 | Tyree Wilson | Texas Tech | SR | OLB | 3 | 2.5 | 14 | 0.83 |
| 4 | Felix Anudike-Uzomah | Kansas St | JR | DE | 4 | 2.5 | 12 | 0.63 |
| 8 | Tyler Lacy | Okla St | SR | DE | 3 | 2.0 | 19 | 0.67 |
| 8 | Davis Mallinger | WVU | FR | S | 3 | 2.0 | 13 | 0.67 |
| 8 | Nathan Latu | Okla St | SR | DE | 4 | 2.0 | 13 | 0.50 |
| 8 | Collin Oliver | Okla St | SO | DE | 4 | 2.0 | 12 | 0.50 |
| 8 | Ben Kopenski | Okla St | SR | DE | 4 | 2.0 | 11 | 0.50 |
| 8 | Danny Stutsman | Oklahoma | SO | LB | 4 | 2.0 | 11 | 0.50 |
| 8 | Philip Blidi | Texas Tech | JR | DL | 3 | 2.0 | 7 | 0.67 |
| 8 | Mason Cobb | Okla St | JR | LB | 3 | 2.0 | 2 | 0.67 |
| 16 | Matt Jones | Baylor | JR | LB | 4 | 1.5 | 15 | 0.38 |
| 16 | Barryn Sorrell | Texas | SO | EDG | 4 | 1.5 | 14 | 0.38 |
| 16 | Jared Bartlett | WVU | SO | BAN | 2 | 1.5 | 13 | 0.75 |
| 16 | Dee Winters | TCU | SR | LB | 5 | 1.5 | 13 | 0.30 |
| 16 | Isaiah Coe | Oklahoma | JR | DL | 4 | 1.5 | 11 | 0.38 |
| 16 | Caleb Sampson | Kansas | SR | DL | 4 | 1.5 | 10 | 0.38 |
| 16 | Krishon Merriweather | Texas Tech | SR | LB | 4 | 1.5 | 10 | 0.38 |
| 16 | Jereme Robinson | Kansas | JR | DL | 4 | 1.5 | 3 | 0.38 |
| 24 | Myles Mendeszoon | Iowa State | FR | LB | 3 | 1.0 | 18 | 0.33 |
| 24 | Kosi Eldridge | Texas Tech | SR | LB | 4 | 1.0 | 15 | 0.25 |
| 24 | Joey Petersen | Iowa State | SO | DE | 3 | 1.0 | 12 | 0.33 |
| 24 | Will McDonald IV | Iowa State | SR | DE | 3 | 1.0 | 12 | 0.33 |
| 24 | Jalen Redmond | Oklahoma | JR | DL | 3 | 1.0 | 11 | 0.33 |
| 24 | Daniel Green | Kansas St | SR | LB | 4 | 1.0 | 11 | 0.25 |
| 24 | Jaylan Ford | Texas | JR | LB | 4 | 1.0 | 11 | 0.25 |
| 24 | Eli Huggins | Kansas St | SR | NG | 4 | 1.0 | 10 | 0.25 |
| 24 | David Ugwoegbu | Oklahoma | SR | LB | 4 | 1.0 | 10 | 0.25 |
| 24 | Brooks Miller | Baylor | SO | LB | 1 | 1.0 | 9 | 1.00 |
| 24 | Johnny Hodges | TCU | JR | LB | 5 | 1.0 | 9 | 0.20 |
| 24 | O'Rien Vance | Iowa State | SR | LB | 3 | 1.0 | 8 | 0.33 |
| 24 | Tony Bradford Jr. | Texas Tech | SR | DL | 4 | 1.0 | 8 | 0.25 |
| 24 | Alfonzo Allen | Baylor | FR | S | 4 | 1.0 | 7 | 0.25 |
| 24 | Brendan Mott | Kansas St | JR | DE | 4 | 1.0 | 7 | 0.25 |
| 24 | Jonah Laulu | Oklahoma | SR | DL | 4 | 1.0 | 7 | 0.25 |
| 24 | Diamonte Tucker-Dorsey | Texas | SR | LB | 4 | 1.0 | 7 | 0.25 |
| 24 | Gerry Vaughn | Iowa State | SR | LB | 3 | 1.0 | 6 | 0.33 |
| 24 | Taijh Alston | WVU | SR | DL | 3 | 1.0 | 6 | 0.33 |
| 24 | Sean Martin | WVU | SO | DL | 3 | 1.0 | 6 | 0.33 |
| 24 | Keondre Coburn | Texas | SR | DL | 4 | 1.0 | 6 | 0.25 |
| 24 | Damonic Williams | TCU | FR | DL | 5 | 1.0 | 5 | 0.20 |
| 24 | VJ Payne | Kansas St | FR | S | 4 | 1.0 | 4 | 0.25 |
| 24 | Brock Martin | Okla St | SR | DE | 4 | 1.0 | 4 | 0.25 |
| 24 | Lyrik Rawls | Okla St | FR | S | 4 | 1.0 | 4 | 0.25 |
| 24 | DaShaun White | Oklahoma | SR | LB | 4 | 1.0 | 4 | 0.25 |
| 24 | Ovie Oghoufo | Texas | SR | EDG | 4 | 1.0 | 4 | 0.25 |