2022 Big 12 Conference Leaders Interceptions - Games in November Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincere Mason | Kansas St | SR | S | 3 | 1 | 37 | 1 | 0.33 |
| 1 | Josh Newton | TCU | JR | CB | 4 | 1 | 57 | 1 | 0.25 |
| 1 | Malachi Ruffin | WVU | JR | DB | 4 | 1 | 43 | 1 | 0.25 |
| 1 | Millard Bradford | TCU | SR | S | 4 | 1 | 36 | 1 | 0.25 |